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Mouse Anti-PLEK2 Recombinant Antibody (5D3) (CBMAB-P2091-YC)

Provided herein is a Mouse monoclonal antibody against Human Pleckstrin 2. The antibody can be used for immunoassay techniques, such as WB.
See all PLEK2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5D3
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 132-353

Target

Full Name
Pleckstrin 2
Introduction
PLEK2 associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease.
Entrez Gene ID
26499
UniProt ID
Q9NYT0
Alternative Names
Pleckstrin 2 Homolog
Function
May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.
Biological Process
Actin cytoskeleton reorganizationManual Assertion Based On ExperimentIBA:GO_Central
Intracellular signal transductionIEA:InterPro
Positive regulation of plasma membrane bounded cell projection assemblyIEA:Ensembl
Cellular Location
Cell projection, lamellipodium membrane
Cytoplasm, cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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