Mouse Anti-PLIN2 Antibody (10BA7) (CBMAB-1490CQ)

Name: Mouse Anti-PLIN2 Antibody (10BA7)
SKU: CBMAB-1490CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

10BA7

Application

ELISA, WB

Immunogen

Recombinant full length protein

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

perilipin 2

Introduction

The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. Diseases associated with PLIN2 include Lipid-Rich Carcinoma and Epithelial-Myoepithelial Carcinoma. Among its related pathways are Metabolism and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha).

Entrez Gene ID

123

UniProt ID

Q99541

Alternative Names

Perilipin 2; Adipose Differentiation-Related Protein; ADFP; adipophilin; ADRP;

Function

Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.

Biological Process

Cellular response to glucose starvationManual Assertion Based On ExperimentIDA:UniProtKB
Lipid droplet disassemblyManual Assertion Based On ExperimentIDA:UniProtKB
Lipid storageManual Assertion Based On ExperimentIDA:UniProtKB
Long-chain fatty acid transportIEA:Ensembl
Positive regulation of sequestering of triglycerideManual Assertion Based On ExperimentIBA:GO_Central
Response to organic cyclic compoundIEA:Ensembl
Response to xenobiotic stimulusIEA:Ensembl

Cellular Location

Membrane
Lipid droplet

PTM

Acylated; primarily with C14, C16 and C18 fatty acids.
Phosphorylation at Tyr-232 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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