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Mouse Anti-PLXDC1 Recombinant Antibody (4B10) (CBMAB-P2189-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
4B10
Antibody Isotype
IgG2b, κ
Application
ELISA, RNAi, WB

Basic Information

Immunogen
PLXDC1 (NP_065138, 313-421 aa) partial recombinant protein with GST tag. Immunogen sequence: CMSSDLTFNC SWCHVLQRCS SGFDRYRQEW MDYGCAQEAE GRMCEDFQDE DHDSASPDTS FSPYDGDLTT TSSSLFIDSL TTEDDTKLNP YAGGDGLQNN LSPKTKGTP
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 313-421

Target

Full Name
plexin domain containing 1
Introduction
PLXDC1 (Plexin Domain Containing 1) is a protein coding gene. Diseases associated with PLXDC1 include Endocardium Disease. An important paralog of the gene is PLXDC2.
Entrez Gene ID
57125
UniProt ID
Q8IUK5
Alternative Names
TEM7; TEM3
Function
Plays a critical role in endothelial cell capillary morphogenesis.
Biological Process
Angiogenesis1 PublicationNAS:UniProtKB
Spinal cord developmentIEA:Ensembl
Cellular Location
Isoform 1
Cell membrane
Cell junction, tight junction
Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.
Isoform 2
Secreted
Isoform 3
Secreted
Isoform 4
Cytoplasm
Topology
Extracellular: 19-426
Helical: 427-447
Cytoplasmic: 448-500
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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