PLXDC1
PLXDC1 (Plexin Domain Containing 1) is a protein coding gene. Diseases associated with PLXDC1 include Endocardium Disease. An important paralog of the gene is PLXDC2.
Full Name
plexin domain containing 1
Function
Plays a critical role in endothelial cell capillary morphogenesis.
Biological Process
Angiogenesis1 PublicationNAS:UniProtKB
Spinal cord developmentIEA:Ensembl
Spinal cord developmentIEA:Ensembl
Cellular Location
Isoform 1
Cell membrane
Cell junction, tight junction
Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.
Isoform 2
Secreted
Isoform 3
Secreted
Isoform 4
Cytoplasm
Cell membrane
Cell junction, tight junction
Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.
Isoform 2
Secreted
Isoform 3
Secreted
Isoform 4
Cytoplasm
Topology
Extracellular: 19-426
Helical: 427-447
Cytoplasmic: 448-500
Helical: 427-447
Cytoplasmic: 448-500
PTM
N-glycosylated.
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Anti-PLXDC1 antibodies
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Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4B10
Application*: E, RNAi, WB
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYJT-1574
Application*: IH, P, WB
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 197C193
Application*: WB, IH, IC, IF, IP, P, C
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1572
Application*: IH, WB
Target: PLXDC1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1570
Application*: E
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1569
Application*: E
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1568
Application*: EC
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1567
Application*: ED
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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