PLXDC1

PLXDC1 (Plexin Domain Containing 1) is a protein coding gene. Diseases associated with PLXDC1 include Endocardium Disease. An important paralog of the gene is PLXDC2.
Full Name
plexin domain containing 1
Function
Plays a critical role in endothelial cell capillary morphogenesis.
Biological Process
Angiogenesis1 PublicationNAS:UniProtKB
Spinal cord developmentIEA:Ensembl
Cellular Location
Isoform 1
Cell membrane
Cell junction, tight junction
Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.
Isoform 2
Secreted
Isoform 3
Secreted
Isoform 4
Cytoplasm
Topology
Extracellular: 19-426
Helical: 427-447
Cytoplasmic: 448-500
PTM
N-glycosylated.
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Anti-PLXDC1 antibodies

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Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4B10
Application*: E, RNAi, WB
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYJT-1574
Application*: IH, P, WB
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 197C193
Application*: WB, IH, IC, IF, IP, P, C
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1572
Application*: IH, WB
Target: PLXDC1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1570
Application*: E
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1569
Application*: E
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1568
Application*: EC
Target: PLXDC1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1567
Application*: ED
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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