Mouse Anti-PLXNB1 Recombinant Antibody (CBYC-P464) (CBMAB-P2202-YC)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Plays a role in GABAergic synapse development (By similarity).
Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development (By similarity).
Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12196628, PubMed:15210733).
Plays a role in axon guidance, invasive growth and cell migration (PubMed:12198496).
Inhibitory synapse assemblyISS:UniProtKB
Intracellular signal transduction1 PublicationNAS:UniProtKB
Negative regulation of cell adhesionManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of osteoblast proliferationISS:BHF-UCL
Neuron projection morphogenesisISS:UniProtKB
Ossification involved in bone maturationISS:BHF-UCL
Positive regulation of axonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of GTPase activityISS:UniProtKB
Positive regulation of phosphatidylinositol 3-kinase signalingISS:UniProtKB
Regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell shapeManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of cytoskeleton organizationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Semaphorin-plexin signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Semaphorin-plexin signaling pathway involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Semaphorin-plexin signaling pathway involved in bone trabecula morphogenesisISS:BHF-UCL
Cell membrane
Isoform 2
Secreted
Isoform 3
Secreted
Helical: 1491-1511
Cytoplasmic: 1512-2135
Proteolytic processing favors heterodimerization with PLXNB2 and SEMA4D binding.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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