Mouse Anti-PODXL2 (AA 33-500) Recombinant Antibody (CBFYE-0081) (CBMAB-E0173-FY)

Name: Mouse Anti-PODXL2 (AA 33-500) Recombinant Antibody (CBFYE-0081)
SKU: CBMAB-E0173-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYE-0081

Application

FC, ICC, CyTOF

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Endoglycan/PODXL2, Gly33-Thr500

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, trehalose

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 33-500

More Infomation

Target

Full Name

Podocalyxin Like 2

Introduction

This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail.

Entrez Gene ID

50512

UniProt ID

Q9NZ53

Alternative Names

EG; PODLX2

Function

Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins.

Biological Process

Leukocyte tethering or rollingManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Membrane

Topology

Extracellular: 33-500
Helical: 501-521
Cytoplasmic: 522-605

PTM

Glycosylated; contains chondroitin sulfate. Displays sialylated O-linked oligosaccharides.
Sulfation is necessary for interaction with SELL. Sialylated O-linked oligosaccharides are necessary for interaction with SELL, SELE and SELP.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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