Mouse Anti-POLB Recombinant Antibody (3H14) (CBMAB-D2169-YC)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Base-excision repairManual Assertion Based On ExperimentIDA:UniProtKB
Base-excision repair, gap-fillingTAS:Reactome
Cellular response to DNA damage stimulusManual Assertion Based On ExperimentIMP:UniProtKB
DNA repairManual Assertion Based On ExperimentTAS:ProtInc
DNA-templated DNA replicationManual Assertion Based On ExperimentTAS:ProtInc
Double-strand break repair via nonhomologous end joiningManual Assertion Based On ExperimentIBA:GO_Central
Homeostasis of number of cellsIEA:Ensembl
Immunoglobulin heavy chain V-D-J recombinationIEA:Ensembl
In utero embryonic developmentIEA:Ensembl
Inflammatory responseIEA:Ensembl
Intrinsic apoptotic signaling pathway in response to DNA damageIEA:Ensembl
Lymph node developmentIEA:Ensembl
Neuron apoptotic processIEA:Ensembl
Pyrimidine dimer repairIEA:Ensembl
Response to ethanolIEA:Ensembl
Response to gamma radiationIEA:Ensembl
Response to hyperoxiaIEA:Ensembl
Salivary gland morphogenesisIEA:Ensembl
Somatic hypermutation of immunoglobulin genesIEA:Ensembl
Spleen developmentIEA:Ensembl
Cytoplasm
Cytoplasmic in normal conditions. Translocates to the nucleus following DNA damage.
Ubiquitinated at Lys-41, Lys-61 and Lys-81: monoubiquitinated by HUWE1/ARF-BP1. Monoubiquitinated protein is then the target of STUB1/CHIP, which catalyzes polyubiquitination from monoubiquitin, leading to degradation by the proteasome. USP47 mediates the deubiquitination of monoubiquitinated protein, preventing polyubiquitination by STUB1/CHIP and its subsequent degradation.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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