Mouse Anti-POLDIP2 Recombinant Antibody (G-10) (CBMAB-P2316-YC)

Name: Mouse Anti-POLDIP2 Recombinant Antibody (G-10)
SKU: CBMAB-P2316-YC
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

G-10

Application

WB, IP, IF, ELISA

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

DNA Polymerase Delta Interacting Protein 2

Introduction

POLDIP2 is a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions.

Entrez Gene ID

26073

UniProt ID

Q9Y2S7

Alternative Names

PDIP38; POLD4; p38

Function

Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites (PubMed:24191025).
May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1) (PubMed:24191025, PubMed:26984527).

Biological Process

Error-free translesion synthesisManual Assertion Based On ExperimentIDA:UniProtKB
Mitochondrion morphogenesisIEA:Ensembl
Mitotic spindle assemblyIEA:Ensembl
Negative regulation of macroautophagyIEA:Ensembl
Positive regulation of actin filament bindingIEA:Ensembl
Positive regulation of focal adhesion assemblyIEA:Ensembl
Positive regulation of mitotic cell cycleIEA:Ensembl
Positive regulation of mitotic cytokinesisIEA:Ensembl
Positive regulation of Rho guanyl-nucleotide exchange factor activityIEA:Ensembl
Vascular associated smooth muscle cell proliferationIEA:Ensembl

Cellular Location

Mitochondrion matrix
Nucleus
Mainly localizes to the mitochondrial matrix; a small fraction localizes in the nucleus.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-POLDIP2 Recombinant Antibody (2765C3a) (CAT#: CBMAB-P2314-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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