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Mouse Anti-PPFIBP1 Recombinant Antibody (CBYJL-2319) (CBMAB-L2618-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Ppfia Binding Protein 1 (PPFIBP1). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all PPFIBP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-2319
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PPFIA binding protein 1
Introduction
PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. PPFIBP1 was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Entrez Gene ID
8496
UniProt ID
Q86W92
Alternative Names
L2; SGT2; hSGT2; hSgt2p
Function
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
Biological Process
Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Neuromuscular junction developmentManual Assertion Based On ExperimentIBA:GO_Central
Synapse organizationManual Assertion Based On ExperimentIBA:GO_Central
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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