Mouse Anti-PPIL2 Recombinant Antibody (2E11) (CBMAB-P2539-YC)

Name: Mouse Anti-PPIL2 Recombinant Antibody (2E11)
SKU: CBMAB-P2539-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

2E11

Application

ELISA

Immunogen

PPIL2 (AAH00022, 1-528 aa) full length recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

peptidylprolyl isomerase (cyclophilin)-like 2

Introduction

PPIL2 (Peptidylprolyl Isomerase Like 2) is a protein coding gene. Among its related pathways are Basigin interactions and Ubiquitin mediated proteolysis. Gene Ontology annotations related to this gene include ligase activity and ubiquitin protein ligase activity.

Entrez Gene ID

23759

UniProt ID

Q13356

Alternative Names

CYC4; CYP60; Cyp-60; UBOX7; hCyP-60

Function

Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation (PubMed:11435423).
May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance (PubMed:15946952).
Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity (PubMed:20676357).

Biological Process

Protein foldingIEA:InterPro
Protein localization to plasma membraneManual Assertion Based On ExperimentIMP:UniProtKB
Protein peptidyl-prolyl isomerizationIEA:InterPro
Protein polyubiquitinationManual Assertion Based On ExperimentIDA:MGI

Cellular Location

Nucleus
May also localize to the cytoplasm and the cell membrane.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-PPIL2 Recombinant Antibody (A-9) (CAT#: CBMAB-P2540-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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