Rabbit Anti-PPL Recombinant Antibody (CBYC-P553) (CBMAB-P2548-YC)

Name: Rabbit Anti-PPL Recombinant Antibody (CBYC-P553)
SKU: CBMAB-P2548-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

CBYC-P553

Application

WB, IHC-P

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Periplakin

Introduction

PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments.

Entrez Gene ID

5493

UniProt ID

O60437

Alternative Names

AW553870

Function

Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling.

Biological Process

Intermediate filament cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
KeratinizationIEA:UniProtKB-KW
Response to mechanical stimulusManual Assertion Based On ExperimentIEP:BHF-UCL
Wound healingManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell junction, desmosome
Cytoplasm, cytoskeleton
Cell membrane
Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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