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Mouse Anti-PPP1R14B Recombinant Antibody (4G2) (CBMAB-P2601-YC)

Provided herein is a Mouse monoclonal antibody against Human Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PPP1R14B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4G2
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
PPP1R14B (NP_619634.1, 64-139 aa) partial recombinant protein with GST tag. Immunogen sequence: ELRKRLNLEE WILEQLTRLY DCQEEEIPEL EIDVDELLDM ESDDARAARV KELLVDCYKP TEAFISGLLD KIRGMQ
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 64-139

Target

Full Name
protein phosphatase 1, regulatory (inhibitor) subunit 14B
Introduction
PPP1R14B (Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B) is a protein coding gene. Among its related pathways are ERK Signaling and Activation of cAMP-Dependent PKA. Gene Ontology annotations related to this gene include protein phosphatase inhibitor activity. An important paralog of the gene is PPP1R14C.
Entrez Gene ID
UniProt ID
Alternative Names
PLCB3N; PHI-1; PNG; SOM172
Function
Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated (By similarity).
Biological Process
Innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Regulation of phosphorylationIEA:InterPro
Cellular Location
Cytoplasm
PTM
Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro) (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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