PPP1R14B

PPP1R14B (Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B) is a protein coding gene. Among its related pathways are ERK Signaling and Activation of cAMP-Dependent PKA. Gene Ontology annotations related to this gene include protein phosphatase inhibitor activity. An important paralog of the gene is PPP1R14C.

Full Name

protein phosphatase 1, regulatory (inhibitor) subunit 14B

Function

Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated (By similarity).

Biological Process

Innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Regulation of phosphorylationIEA:InterPro

Cellular Location

Cytoplasm

PTM

Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro) (By similarity).

Anti-PPP1R14B antibodies

Mouse Anti-PPP1R14B Recombinant Antibody (C-11) (CBMAB-P2602-YC)

Datasheet

SDS

Target: PPP1R14B

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: C-11

Application*: WB, IP, IF, E

Mouse Anti-PPP1R14B Recombinant Antibody (4G2) (CBMAB-P2601-YC)

Datasheet

SDS

Target: PPP1R14B

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4G2

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)