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PPP1R14B

PPP1R14B (Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B) is a protein coding gene. Among its related pathways are ERK Signaling and Activation of cAMP-Dependent PKA. Gene Ontology annotations related to this gene include protein phosphatase inhibitor activity. An important paralog of the gene is PPP1R14C.

Full Name

protein phosphatase 1, regulatory (inhibitor) subunit 14B

Function

Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated (By similarity).

Biological Process

Innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Regulation of phosphorylationIEA:InterPro

Cellular Location

Cytoplasm

PTM

Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro) (By similarity).

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Anti-PPP1R14B antibodies

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Mouse Anti-PPP1R14B Recombinant Antibody (C-11) (CBMAB-P2602-YC)

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Target: PPP1R14B

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: C-11

Application*: WB, IP, IF, E

Mouse Anti-PPP1R14B Recombinant Antibody (4G2) (CBMAB-P2601-YC)

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Target: PPP1R14B

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4G2

Application*: E, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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