PPP1R14B

PPP1R14B (Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B) is a protein coding gene. Among its related pathways are ERK Signaling and Activation of cAMP-Dependent PKA. Gene Ontology annotations related to this gene include protein phosphatase inhibitor activity. An important paralog of the gene is PPP1R14C.
Full Name
protein phosphatase 1, regulatory (inhibitor) subunit 14B
Function
Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated (By similarity).
Biological Process
Innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Regulation of phosphorylationIEA:InterPro
Cellular Location
Cytoplasm
PTM
Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro) (By similarity).
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Anti-PPP1R14B antibodies

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Target: PPP1R14B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: C-11
Application*: WB, IP, IF, E
Target: PPP1R14B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4G2
Application*: E, WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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