Rabbit Anti-PPP2R2A Recombinant Antibody (F.722.1) (CBMAB-P2633-YC)

Name: Rabbit Anti-PPP2R2A Recombinant Antibody (F.722.1)
SKU: CBMAB-P2633-YC
Rating: 5 (1 reviews)

See all PPP2R2A antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

F.722.1

Application

IHC-P, IP, WB

Immunogen

Synthetic peptide corresponding to the sequence of human PP2A B subunit

Specificity

Human, Cattle, Chicken, Friut fly, Mouse, Pig, Rat

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

10 mM HEPES with 150 mM sodium chloride, 100 μg/mL BSA, 50% glycerol, 0.02% sodium azide, pH 7.5

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Protein Phosphatase 2 Regulatory Subunit Balpha

Introduction

PPP2R2A belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity.

Entrez Gene ID

Human	5520
Mouse	71978
Rat	117104
Chicken	419523
Cattle	508045
Pig	397090

UniProt ID

Human	P63151
Mouse	Q6P1F6
Rat	P36876
Chicken	Q5ZLP4
Cattle	F1MG56
Pig	Q29090

Alternative Names

B55ALPHA; B55A; 2410004D02Rik; PR52A; PR55alpha; PR55A; mKIAA1541

Function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint (PubMed:33108758).

Biological Process

Protein dephosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Response to morphineIEA:Ensembl

Cellular Location

cytosol
glutamatergic synapse
nucleoplasm
protein phosphatase type 2A complex

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rabbit Anti-PPP2R2A Recombinant Antibody (F.722.1)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry