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Mouse Anti-PPP2R3B Recombinant Antibody (2E12) (CBMAB-P2640-YC)

Provided herein is a Mouse monoclonal antibody against Human Protein Phosphatase 2 Regulatory Subunit B''Beta. The antibody can be used for immunoassay techniques, such as ELISA, ICC, IF, IP.
See all PPP2R3B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2E12
Antibody Isotype
IgG2b, κ
Application
ELISA, ICC, IF, IP

Basic Information

Immunogen
PPP2R3B (AAH11180, 1-225 aa) full length recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PPP2R3B
Introduction
Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme.
Entrez Gene ID
28227
UniProt ID
Q9Y5P8
Alternative Names
NYREN8; PPP2R3L; PPP2R3LY; PR48; PR70
Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Biological Process
Protein dephosphorylationISS:UniProtKB
Regulation of cell cycleManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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