PPP2R3B

Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
Full Name
PPP2R3B
Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Biological Process
Protein dephosphorylationISS:UniProtKB
Regulation of cell cycleManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
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Anti-PPP2R3B antibodies

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Mouse Anti-PPP2R3B Recombinant Antibody (1F4) (CBMAB-A6980-LY)

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Target: PPP2R3B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1F4
Application*: WB, E
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Mouse Anti-PPP2R3B Recombinant Antibody (2E12) (CBMAB-P2640-YC)

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Target: PPP2R3B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2E12
Application*: E, IC, IF, IP
Datasheet SDS

PPP2R3B Matched Antibody Pair (919) (APMAB-919LY)

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Target: PPP2R3B
Specificity: Human
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PPP2R3B Matched Antibody Pair (918) (APMAB-918LY)

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Target: PPP2R3B
Specificity: Human
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PPP2R3B Matched Antibody Pair (917) (APMAB-917LY)

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Target: PPP2R3B
Specificity: Human
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PPP2R3B Matched Antibody Pair (916) (APMAB-916LY)

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Target: PPP2R3B
Specificity: Human
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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