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Mouse Anti-PPP2R5D Recombinant Antibody (H5D12) (CBMAB-1695-CN)

This product is a mouse antibody that recognizes PPP2R5D of human. The antibody H5D12 can be used for immunoassay techniques such as: IP, WB.
See all PPP2R5D antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
H5D12
Antibody Isotype
IgG1
Application
IP, WB

Basic Information

Immunogen
Recombinant fragment (proprietary-tag) within Human PPP2R5D (N terminal).
Specificity
Human, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
99% PBS
Preservative
0.01% Thimerosal
Concentration
1 mg/mL
Storage
Store at +4°C.

Target

Full Name
protein phosphatase 2, regulatory subunit B', delta isoform
Introduction
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Entrez Gene ID
Human5528
Rat363193
UniProt ID
HumanQ14738
RatF1MAA3
Alternative Names
B56D; MRD35; B56delta
Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Biological Process
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of protein dephosphorylationIEA:Ensembl
Protein dephosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Signal transductionIEA:InterPro
Cellular Location
Cytoplasm
Nucleus
Nuclear in interphase, nuclear during mitosis.
Involvement in disease
Intellectual developmental disorder, autosomal dominant 35 (MRD35):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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