Mouse Anti-PPP2R5D Recombinant Antibody (H5D12) (CBMAB-1695-CN)

Name: Mouse Anti-PPP2R5D Recombinant Antibody (H5D12)
SKU: CBMAB-1695-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

H5D12

Application

IP, WB

Immunogen

Recombinant fragment (proprietary-tag) within Human PPP2R5D (N terminal).

Specificity

Human, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

99% PBS

Preservative

0.01% Thimerosal

Concentration

1 mg/mL

Storage

Store at +4°C.

More Infomation

Target

Full Name

protein phosphatase 2, regulatory subunit B', delta isoform

Introduction

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Entrez Gene ID

Human	5528
Rat	363193

UniProt ID

Human	Q14738
Rat	F1MAA3

Alternative Names

B56D; MRD35; B56delta

Function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Biological Process

Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of protein dephosphorylationIEA:Ensembl
Protein dephosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Signal transductionIEA:InterPro

Cellular Location

Cytoplasm
Nucleus
Nuclear in interphase, nuclear during mitosis.

Involvement in disease

Intellectual developmental disorder, autosomal dominant 35 (MRD35):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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