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PPP2R5D

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Full Name
protein phosphatase 2, regulatory subunit B', delta isoform
Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Biological Process
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of protein dephosphorylationIEA:Ensembl
Protein dephosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Signal transductionIEA:InterPro
Cellular Location
Cytoplasm
Nucleus
Nuclear in interphase, nuclear during mitosis.
Involvement in disease
Intellectual developmental disorder, autosomal dominant 35 (MRD35):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.

Anti-PPP2R5D antibodies

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Target: PPP2R5D
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5E7
Application*: P
Target: PPP2R5D
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4E12
Application*: E, WB
Target: PPP2R5D
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A3
Application*: E, IF, WB
Target: PPP2R5D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10D11
Application*: WB
Target: PPP2R5D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: H5D12
Application*: IP, WB
Target: PPP2R5D
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EPR15617-50
Application*: P, IP, WB
Target: PPP2R5D
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EPR15617
Application*: WB, P, F, IF, IP
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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