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Mouse Anti-PPY Recombinant Antibody (6) (CBMAB-P2673-YC)

Provided herein is a Mouse monoclonal antibody against Human Pancreatic Polypeptide. The antibody can be used for immunoassay techniques, such as ELISA.
See all PPY antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Immunogen
Synthetic human Pancreatic Polypeptide
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
10 mM phosphate buffer, pH 7.4, containing 0.5 M sodium chloride and 15 mM sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
pancreatic polypeptide
Introduction
PPY is a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa.
Entrez Gene ID
5539
UniProt ID
P01298
Alternative Names
PNP; PP
Function
Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.
The physiological role for the icosapeptide has not yet been elucidated.
Biological Process
Feeding behaviorManual Assertion Based On ExperimentIBA:GO_Central
Neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Protein secretionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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