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PPY

PPY is a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa.
Full Name
pancreatic polypeptide
Function
Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.
The physiological role for the icosapeptide has not yet been elucidated.
Biological Process
Feeding behaviorManual Assertion Based On ExperimentIBA:GO_Central
Neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Protein secretionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
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Anti-PPY antibodies

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Mouse Anti-PPY Recombinant Antibody (CBYC-P584) (CBMAB-P2677-YC)

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Target: PPY
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYC-P584
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-PPY Recombinant Antibody (CBYC-P583) (CBMAB-P2676-YC)

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Target: PPY
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-P583
Application*: E, WB, F
Datasheet SDS

Mouse Anti-PPY Recombinant Antibody (B-2) (CBMAB-P2675-YC)

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Target: PPY
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: B-2
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-PPY Recombinant Antibody (CBYC-P582) (CBMAB-P2674-YC)

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Target: PPY
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYC-P582
Application*: WB
Datasheet SDS

Mouse Anti-PPY Recombinant Antibody (6) (CBMAB-P2673-YC)

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Target: PPY
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6
Application*: E
Datasheet SDS

Mouse Anti-PPY Recombinant Antibody (327) (CBMAB-P2672-YC)

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Target: PPY
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 327
Application*: WB
Datasheet SDS

Mouse Anti-PPY Recombinant Antibody (2G5D12) (CBMAB-P2671-YC)

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Target: PPY
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2G5D12
Application*: WB, F, E, MC
Datasheet SDS

Mouse Anti-PPY Recombinant Antibody (2C10) (CBMAB-P2670-YC)

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Target: PPY
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C10
Application*: E, WB
Datasheet SDS

Mouse Anti-PPY Recombinant Antibody (CBT2517) (V2LY-0625-LY2795)

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Target: PPY
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2517
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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