Mouse Anti-PRELID1 Recombinant Antibody (CBYC-P602) (CBMAB-P2754-YC)

Name: Mouse Anti-PRELID1 Recombinant Antibody (CBYC-P602)
SKU: CBMAB-P2754-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYC-P602

Application

ELISA, IHC, WB

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

PBS, pH 7.2, 0.09% sodium azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 3-101

More Infomation

Target

Full Name

PRELI domain containing 1

Introduction

PRELID1 is a member of the late embryogenesis abundant motif-containing protein family. The encoded protein is localized to mitochondria and may function as a cytoprotectant by regulating cell death and differentiation.

Entrez Gene ID

27166

UniProt ID

Q9Y255

Alternative Names

CGI-106; PRELI; PX19; SBBI12

Function

Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.

Biological Process

Apoptotic processIEA:UniProtKB-KW
Intermembrane lipid transferIEA:GOC
Negative regulation of apoptotic processManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of mitochondrial membrane potentialManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of release of cytochrome c from mitochondriaManual Assertion Based On ExperimentIDA:UniProtKB
Phospholipid transportManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cellular respirationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of phospholipid transportManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of T cell apoptotic processManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of membrane lipid distributionManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of mitochondrial membrane potentialManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of T cell differentiationManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Mitochondrion
Mitochondrion intermembrane space

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-PRELID1 Monoclonal Antibody (6G1) (CAT#: CBMAB-1446-YC)

Mouse Anti-PRELID1 Recombinant Antibody (7B4) (CAT#: CBMAB-1696-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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