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Rabbit Anti-PRKD3 Recombinant Antibody (11C1061) (CBMAB-P2872-YC)

Provided herein is a Rabbit monoclonal antibody against Human Protein Kinase D3. The antibody can be used for immunoassay techniques, such as IP, WB.
See all PRKD3 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
11C1061
Antibody Isotype
IgG
Application
IP, WB

Basic Information

Immunogen
Synthetic peptide corresponding to residues surrounding Ala880 of human PKD3/PKCv.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
protein kinase D3
Introduction
PRKD3 belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization.
Entrez Gene ID
23683
UniProt ID
O94806
Alternative Names
PKD3; EPK2; nPKC-NU; PKC-NU; PRKCN
Function
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
Biological Process
Protein kinase C-activating G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Protein kinase D signalingManual Assertion Based On ExperimentIBA:GO_Central
Protein phosphorylationManual Assertion Based On ExperimentTAS:ProtInc
Sphingolipid biosynthetic processTAS:Reactome
Cellular Location
Cytoplasm
Membrane
Translocation to the cell membrane is required for kinase activation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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