Rat Anti-PROCR Recombinant Antibody (CBYC-P648) (CBMAB-P2976-YC)

Name: Rat Anti-PROCR Recombinant Antibody (CBYC-P648)
SKU: CBMAB-P2976-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

CBYC-P648

Application

Immunogen

NS0-derived, recombinant mouse EPCR aa17-214 Q64695

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 17-214

More Infomation

Target

Full Name

protein C receptor, endothelial (EPCR)

Introduction

PROCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C.

Entrez Gene ID

19124

UniProt ID

Q64695

Alternative Names

CCCA; CCD41; EPCR

Function

Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.

Biological Process

Blood coagulationIEA:UniProtKB-KW
Negative regulation of coagulationManual Assertion Based On ExperimentIMP:BHF-UCL

Cellular Location

Membrane

Involvement in disease

N-glycosylated.
A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.

Topology

Extracellular: 18-210
Helical: 211-231
Cytoplasmic: 232-238

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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