PROCR
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. [provided by RefSeq]
Full Name
protein C receptor, endothelial (EPCR)
Function
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
Biological Process
Blood coagulationIEA:UniProtKB-KW
Negative regulation of coagulationManual Assertion Based On ExperimentIMP:BHF-UCL
Negative regulation of coagulationManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
Membrane
Involvement in disease
N-glycosylated.
A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
Topology
Extracellular: 18-210
Helical: 211-231
Cytoplasmic: 232-238
Helical: 211-231
Cytoplasmic: 232-238
View more
Anti-PROCR antibodies
+ Filters
Loading...
CompareTarget: PROCR
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: RCR-16
Application*: F
Target: PROCR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G8
Application*: WB
Target: PROCR
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4B9D
Application*: F
Target: PROCR
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYE-1608
Application*: WB, IH, P
Target: PROCR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2544
Application*: WB
Target: PROCR
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBHb217
Application*: FC, FuncS, IP, WB
Target: PROCR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBHb216
Application*: FC, IHC-F, FuncS
Target: PROCR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M3
Application*: WB, E
Target: PROCR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M1-5A10
Application*: SE, E
Target: PROCR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: RCR-379
Application*: FN, C
Target: PROCR
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: RCR-227
Application*: F
Target: PROCR
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0143
Application*: F, FN, IP, WB
Target: PROCR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYA-0142
Application*: F, C, FN
Target: PROCR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJC-4322
Application*: C
Target: PROCR
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: CBWJC-2376
Application*: F, FN, IH, N
Target: PROCR
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0815
Application*: F
Target: PROCR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYC-P648
Application*: F
Target: PROCR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M2
Application*: IF
Target: PROCR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6D701
Application*: F, IC, IH
Target: PROCR
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 13E1
Application*: IH
Target: PROCR
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 12C4
Application*: WB
Target: PROCR
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: CBFYE-1607
Application*: E
Target: PROCR
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYE-1605
Application*: WB
Target: PROCR
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYE-1604
Application*: WB, IH
Target: PROCR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYE-0099
Application*: F
Target: PROCR
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYE-0056
Application*: E, F
Target: PROCR
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: RCR-252
Application*: E, F, IP, WB
Target: PROCR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Rat
Clone: LMR-42
Application*: F, C
More Infomation
Hot products 
-
Mouse Anti-AP4E1 Recombinant Antibody (32) (CBMAB-A2996-YC)
-
Mouse Anti-AMH Recombinant Antibody (5/6) (CBMAB-A2527-YC)
-
Mouse Anti-CD24 Recombinant Antibody (SN3) (CBMAB-C1037-CQ)
-
Mouse Anti-CD2AP Recombinant Antibody (BR083) (CBMAB-BR083LY)
-
Mouse Anti-DISP2 Monoclonal Antibody (F66A4B1) (CBMAB-1112CQ)
-
Mouse Anti-EGR1 Recombinant Antibody (CBWJZ-100) (CBMAB-Z0289-WJ)
-
Mouse Anti-ALB Recombinant Antibody (V2-55272) (CBMAB-H0819-FY)
-
Rabbit Anti-ATF4 Recombinant Antibody (D4B8) (CBMAB-A3872-YC)
-
Mouse Anti-ABL2 Recombinant Antibody (V2-179121) (CBMAB-A0364-YC)
-
Mouse Anti-AFDN Recombinant Antibody (V2-58751) (CBMAB-L0408-YJ)
-
Rat Anti-CD34 Recombinant Antibody (MEC 14.7) (CBMAB-C10196-LY)
-
Mouse Anti-CAT Recombinant Antibody (724810) (CBMAB-C8431-LY)
-
Rat Anti-CD300A Recombinant Antibody (172224) (CBMAB-C0423-LY)
-
Mouse Anti-DLL4 Recombinant Antibody (D1090) (CBMAB-D1090-YC)
-
Mouse Anti-ADRB2 Recombinant Antibody (V2-180026) (CBMAB-A1420-YC)
-
Mouse Anti-BANF1 Recombinant Antibody (3F10-4G12) (CBMAB-A0707-LY)
-
Rabbit Anti-AKT2 (Phosphorylated S474) Recombinant Antibody (V2-556130) (PTM-CBMAB-0605LY)
-
Mouse Anti-2C TCR Recombinant Antibody (V2-1556) (CBMAB-0951-LY)
-
Mouse Anti-AHCYL1 Recombinant Antibody (V2-180270) (CBMAB-A1703-YC)
-
Mouse Anti-ADV Recombinant Antibody (V2-503423) (CBMAB-V208-1364-FY)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
Online Inquiry