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Rat Anti-PROCR Recombinant Antibody (RCR-252) (CBMAB-E2265-FY)

This product is rat antibody that recognizes PROCR. The antibody RCR-252 can be used for immunoassay techniques such as: ELISA, FC, IP, WB.
See all PROCR antibodies
Published Data
Fig.1 EPCR mRNA in neutrophils and monocytes. 1 μg total RNA from each sample was reverse transcribed into cDNA and amplified for the EPCR gene using PCR. EPCR is represented by the 409–base pair product.
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Summary

Host Animal
Rat
Specificity
Human
Clone
RCR-252
Antibody Isotype
IgG1
Application
ELISA, FC, IP, WB

Basic Information

Immunogen
Human EPCR-positive RE-1 cells
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% BSA
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
protein C receptor, endothelial (EPCR)
Introduction
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C.
Entrez Gene ID
10544
UniProt ID
Q9UNN8
Alternative Names
CCCA; EPCR; CCD41
Function
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
Biological Process
Blood coagulationIEA:UniProtKB-KW
Negative regulation of coagulationManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
Membrane
Involvement in disease
N-glycosylated.
A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
Topology
Extracellular: 18-210
Helical: 211-231
Cytoplasmic: 232-238
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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