Mouse Anti-PROCR (AA 1-210) Recombinant Antibody (CBFYE-1608) (CBMAB-E2267-FY)

Name: Mouse Anti-PROCR (AA 1-210) Recombinant Antibody (CBFYE-1608)
SKU: CBMAB-E2267-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBFYE-1608

Application

WB, IHC, IHC-P

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-210 of human PROCR produced in HEK293T cell

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 1-210

More Infomation

Target

Full Name

protein C receptor, endothelial (EPCR)

Introduction

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C.

Entrez Gene ID

10544

UniProt ID

Q9UNN8

Alternative Names

CCCA; EPCR; CCD41

Function

Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.

Biological Process

Blood coagulationIEA:UniProtKB-KW
Negative regulation of coagulationManual Assertion Based On ExperimentIMP:BHF-UCL

Cellular Location

Membrane

Involvement in disease

N-glycosylated.
A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.

Topology

Extracellular: 18-210
Helical: 211-231
Cytoplasmic: 232-238

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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