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Rat Anti-PROCR Recombinant Antibody (CBWJC-4322) (CBMAB-C5687WJ)

This product is a Rat antibody that recognizes PROCR. This antibody CBWJC-4322 can be used for immunoassay techniques such as: IHC-Fr.
See all PROCR antibodies

Summary

Host Animal
Rat
Specificity
Human
Clone
CBWJC-4322
Antibody Isotype
IgG2a
Application
IHC-Fr

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
protein C receptor, endothelial (EPCR)
Introduction
PROCR (Protein C Receptor) is a Protein Coding gene. Diseases associated with PROCR include Purpura Fulminans and Arteriovenous Fistula. Among its related pathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades.
Entrez Gene ID
10544
UniProt ID
Q9UNN8
Alternative Names
Q9UNN8
Function
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
Biological Process
Blood coagulationIEA:UniProtKB-KW
Negative regulation of coagulationManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
Membrane
Involvement in disease
N-glycosylated.
A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
Topology
Extracellular: 18-210
Helical: 211-231
Cytoplasmic: 232-238
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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