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Mouse Anti-PRPS2 Recombinant Antibody (4C1) (CBMAB-P3033-YC)

Provided herein is a Mouse monoclonal antibody against Human Phosphoribosyl Pyrophosphate Synthetase 2. The antibody can be used for immunoassay techniques, such as ELISA, RNAi, WB.
See all PRPS2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4C1
Antibody Isotype
IgG2a, κ
Application
ELISA, RNAi, WB

Basic Information

Immunogen
PRPS2 (NP_002756, 160-269 aa) partial recombinant protein with GST tag. Immunogen sequence: AEWKNCIIVS PDAGGAKRVT SIADRLNVEF ALIHKERKKA NEVDRMVLVG DVKDRVAILV DDMADTCGTI CHAADKLLSA GATKVYAILT HGIFSGPAIS RINNAAFEAV
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 160-269

Target

Full Name
phosphoribosyl pyrophosphate synthetase 2
Introduction
PRPS2 is a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate.
Entrez Gene ID
5634
UniProt ID
P11908
Alternative Names
PRSII
Function
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
Biological Process
5-phosphoribose 1-diphosphate biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
AMP biosynthetic processIEA:Ensembl
Animal organ regenerationIEA:Ensembl
Nucleobase-containing compound metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Pentose-phosphate shuntIEA:Ensembl
PhosphorylationIEA:UniProtKB-KW
Purine nucleotide biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytoplasm
cytosol
ribose phosphate diphosphokinase complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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