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PRPS2

PRPS2 is a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate.

Full Name

phosphoribosyl pyrophosphate synthetase 2

Function

Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.

Biological Process

5-phosphoribose 1-diphosphate biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
AMP biosynthetic processIEA:Ensembl
Animal organ regenerationIEA:Ensembl
Nucleobase-containing compound metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Pentose-phosphate shuntIEA:Ensembl
PhosphorylationIEA:UniProtKB-KW
Purine nucleotide biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytoplasm
cytosol
ribose phosphate diphosphokinase complex

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Anti-PRPS2 antibodies

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Mouse Anti-PRPS2 Recombinant Antibody (CBYC-P666) (CBMAB-P3034-YC)

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Target: PRPS2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYC-P666

Application*: E, WB

Mouse Anti-PRPS2 Recombinant Antibody (4C1) (CBMAB-P3033-YC)

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Target: PRPS2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4C1

Application*: E, RNAi, WB

Human Recombinant PRPS2 protein, His Tag (V2LY-0526-LY6355)

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Target: PRPS2

Expressed Host: E. coli

Sequence: Amino Acid: 1-318

Tag: His Tag

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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