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Mouse Anti-PSAT1 Recombinant Antibody (CBYC-P679) (CBMAB-P3102-YC)

Provided herein is a Mouse monoclonal antibody against Human Phosphoserine aminotransferase 1. The antibody can be used for immunoassay techniques, such as IHC-P, WB.
See all PSAT1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBYC-P679
Antibody Isotype
IgG2b
Application
IHC-P, WB

Basic Information

Immunogen
Recombinant protein encompassing a sequence within the center region of human PSAT1.
Specificity
Human, Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PSAT1
Introduction
PSAT1 is a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency.
Entrez Gene ID
Human29968
Mouse107272
UniProt ID
HumanQ9Y617
MouseQ99K85
Alternative Names
EPIP; PSAT; PSA; NLS2; PSATD
Function
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Biological Process
L-serine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Pyridoxine biosynthetic process1 PublicationNAS:UniProtKB
Cellular Location
Phosphoserine aminotransferase deficiency (PSATD):
Characterized biochemically by low plasma and cerebrospinal fluid concentrations of serine and glycine and clinically by intractable seizures, acquired microcephaly, hypertonia, and psychomotor retardation.
Neu-Laxova syndrome 2 (NLS2):
A form of Neu-Laxova syndrome, a lethal, autosomal recessive multiple malformation syndrome characterized by ichthyosis, marked intrauterine growth restriction, microcephaly, short neck, limb deformities, hypoplastic lungs, edema, and central nervous system anomalies. These include lissencephaly, cerebellar hypoplasia and/or abnormal/agenesis of the corpus callosum. Abnormal facial features include severe proptosis with ectropion, hypertelorism, micrognathia, flattened nose, and malformed ears.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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