Sign in or Register   Sign in or Register
  |  

Rabbit Anti-PSMA2 Recombinant Antibody (D3A4) (CBMAB-P3137-YC)

Provided herein is a Rabbit monoclonal antibody against Human Proteasome Subunit Alpha 2. The antibody can be used for immunoassay techniques, such as WB.
See all PSMA2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat, Monkey, Chicken, Frog, Zebrafish, Cattle, Horse
Clone
D3A4
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Human, Mouse, Rat, Monkey, Chicken, Frog, Zebrafish, Cattle, Horse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Proteasome Subunit Alpha 2
Introduction
PSMA2 (Proteasome Subunit Alpha 2) is a protein coding gene. Among its related pathways are Cell Cycle, Mitotic and RET signaling. Gene Ontology annotations related to this gene include endopeptidase activity and threonine-type endopeptidase activity.
Entrez Gene ID
Human5683
Mouse19166
Rat29669
Chicken420772
Cattle539141
Frog549136
Monkey701683
Horse100064293
UniProt ID
HumanP25787
MouseP49722
RatP17220
ChickenA0A1D5PHL0
CattleQ3T0Y5
FrogP24495
ZebrafishQ4VBR8
MonkeyF7AC21
HorseF6TCI4
Alternative Names
Lmpc3
Function
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Biological Process
Proteasomal protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Proteasome-mediated ubiquitin-dependent protein catabolic processISS:FlyBase
Response to virusManual Assertion Based On ExperimentIEP:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9 (PubMed:34711951).
Colocalizes with TRIM5 in cytoplasmic bodies (By similarity).
PTM
Phosphorylated on tyrosine residues; which may be important for nuclear import.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-PSMA2 Recombinant Antibody (D3A4)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare