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Rabbit Anti-PSME1 Recombinant Antibody (D1C10) (CBMAB-P3248-YC)

Provided herein is a Rabbit monoclonal antibody against Human Proteasome Activator Subunit 1. The antibody can be used for immunoassay techniques, such as WB, IP.
See all PSME1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat, Monkey, Cattle, Dog, Pig
Clone
D1C10
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Specificity
Human, Mouse, Rat, Monkey, Cattle, Dog, Pig
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Proteasome Activator Subunit 1
Introduction
SME1 (Proteasome Activator Subunit 1) is a protein coding gene. Among its related pathways are Cell Cycle, Mitotic and RET signaling. Gene Ontology annotations related to this gene include endopeptidase activator activity. An important paralog of the gene is PSME2.
Entrez Gene ID
Human5720
Mouse19186
Rat29630
Pig397572
Monkey714364
Dog480256
Cattle510041
UniProt ID
HumanQ06323
MouseP97371
RatQ63797
PigQ64L94
MonkeyF7FF62
DogF6UY11
CattleQ4U5R3
Alternative Names
AW413925; PA28a
Function
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
Biological Process
Antigen processing and presentation of exogenous antigenIEA:Ensembl
Positive regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Regulation of G1/S transition of mitotic cell cycleManual Assertion Based On ExperimentIBA:GO_Central
Regulation of proteasomal protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytoplasm
cytosol
extracellular exosome
nucleoplasm
proteasome activator complex
proteasome complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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