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Mouse Anti-PSME2 Recombinant Antibody (1G4) (CBMAB-P3250-YC)

Provided herein is a Mouse monoclonal antibody against Human Proteasome Activator Subunit 2. The antibody can be used for immunoassay techniques, such as ELISA, IHC-P, IP, WB.
See all PSME2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1G4
Antibody Isotype
IgG2a, κ
Application
ELISA, IHC-P, IP, WB

Basic Information

Immunogen
PSME2 (NP_002809, 1-90 aa) partial recombinant protein with GST tag. Immunogen sequence: MAKPCGVRLS GEARKQVEVF RQNLFQEAEE FLYRFLPQKI IYLNQLLQED SLNVADLTSL RAPLDIPIPD PPPKDDEMET DKQEKKEVHK
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-90

Target

Full Name
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Introduction
PSME2 (Proteasome Activator Subunit 2) is a protein coding gene. Diseases associated with PSME2 include Ulceroglandular Tularemia. Among its related pathways are Cell Cycle, Mitotic and RET signaling. An important paralog of the gene is PSME1.
Entrez Gene ID
5721
UniProt ID
Q9UL46
Alternative Names
AA589371; AI788882; PA28b
Function
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
Biological Process
Positive regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Regulation of G1/S transition of mitotic cell cycleManual Assertion Based On ExperimentIBA:GO_Central
Regulation of proteasomal protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytoplasm
cytosol
extracellular exosome
membrane
nucleoplasm
proteasome activator complex
proteasome complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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