Mouse Anti-PSME2 Recombinant Antibody (CBYC-P724) (CBMAB-P3253-YC)

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Basic Information

Host Animal
Mouse
Clone
CBYC-P724
Application
IF, ELISA, WB
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Introduction
PSME2 (Proteasome Activator Subunit 2) is a protein coding gene. Diseases associated with PSME2 include Ulceroglandular Tularemia. Among its related pathways are Cell Cycle, Mitotic and RET signaling.
Entrez Gene ID
UniProt ID
Alternative Names
PA28B; PA28beta; REGbeta
Function
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
Biological Process
Positive regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Regulation of G1/S transition of mitotic cell cycleManual Assertion Based On ExperimentIBA:GO_Central
Regulation of proteasomal protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytoplasm
cytosol
extracellular exosome
membrane
nucleoplasm
proteasome activator complex
proteasome complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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