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Mouse Anti-PSMG1 Recombinant Antibody (4F2) (CBMAB-P3262-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
4F2
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
DSCR2 (AAH03619, 1-289 aa) full length recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
proteasome (prosome, macropain) assembly chaperone 1
Introduction
PSMG1 (Proteasome Assembly Chaperone 1) is a protein coding gene. Diseases associated with PSMG1 include Down Syndrome and Thrombasthenia. Gene Ontology annotations related to this gene include proteasome binding.
Entrez Gene ID
8624
UniProt ID
O95456
Alternative Names
C21LRP; DSCR2; LRPC21; PAC-1; PAC1
Function
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
Biological Process
Cerebellar granule cell precursor proliferationIEA:Ensembl
Chaperone-mediated protein complex assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Proteasome core complex assemblyManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Endoplasmic reticulum
PTM
Degraded by the proteasome upon completion of 20S proteasome maturation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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