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PSMG1

PSMG1 (Proteasome Assembly Chaperone 1) is a protein coding gene. Diseases associated with PSMG1 include Down Syndrome and Thrombasthenia. Gene Ontology annotations related to this gene include proteasome binding.

Full Name

proteasome (prosome, macropain) assembly chaperone 1

Function

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

Biological Process

Cerebellar granule cell precursor proliferationIEA:Ensembl
Chaperone-mediated protein complex assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Proteasome core complex assemblyManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm
Endoplasmic reticulum

PTM

Degraded by the proteasome upon completion of 20S proteasome maturation.

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Anti-PSMG1 antibodies

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Mouse Anti-PSMG1 Recombinant Antibody (4F2) (CBMAB-P3262-YC)

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Target: PSMG1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4F2

Application*: E

Mouse Anti-PSMG1 Recombinant Antibody (4F2)

Mouse Anti-PSMG1 Recombinant Antibody (V2-358670) (CBMAB-P3261-YC)

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Target: PSMG1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: V2-358670

Application*: E, WB

Mouse Anti-PSMG1 Recombinant Antibody (V2-358670)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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