PSMG1

PSMG1 (Proteasome Assembly Chaperone 1) is a protein coding gene. Diseases associated with PSMG1 include Down Syndrome and Thrombasthenia. Gene Ontology annotations related to this gene include proteasome binding.

Full Name

proteasome (prosome, macropain) assembly chaperone 1

Function

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

Biological Process

Cerebellar granule cell precursor proliferationIEA:Ensembl
Chaperone-mediated protein complex assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Proteasome core complex assemblyManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm
Endoplasmic reticulum

PTM

Degraded by the proteasome upon completion of 20S proteasome maturation.

Anti-PSMG1 antibodies

Mouse Anti-PSMG1 Recombinant Antibody (4F2) (CBMAB-P3262-YC)

Datasheet

SDS

Target: PSMG1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4F2

Application*: E

Mouse Anti-PSMG1 Recombinant Antibody (V2-358670) (CBMAB-P3261-YC)

Datasheet

SDS

Target: PSMG1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: V2-358670

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)