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Mouse Anti-PTBP3 Recombinant Antibody (4C9) (CBMAB-P3290-YC)

Provided herein is a Mouse monoclonal antibody against Human Polypyrimidine tract binding protein 3. The antibody can be used for immunoassay techniques, such as ELISA, IF, WB.
See all PTBP3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4C9
Antibody Isotype
IgG1, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
ROD1 (NP_005147, 16-115 aa) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Polypyrimidine tract binding protein 3
Introduction
PTBP3 binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro.
Entrez Gene ID
9991
UniProt ID
O95758
Alternative Names
ROD1
Function
RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
Biological Process
Anatomical structure morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Erythrocyte maturationIEA:UniProtKB-KW
mRNA processingIEA:UniProtKB-KW
Negative regulation of RNA splicingManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of cell differentiationIEA:InterPro
Regulation of RNA splicingManual Assertion Based On ExperimentIBA:GO_Central
RNA splicingIEA:UniProtKB-KW
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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