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PTBP3

PTBP3 binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro.
Full Name
Polypyrimidine tract binding protein 3
Function
RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
Biological Process
Anatomical structure morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Erythrocyte maturationIEA:UniProtKB-KW
mRNA processingIEA:UniProtKB-KW
Negative regulation of RNA splicingManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of cell differentiationIEA:InterPro
Regulation of RNA splicingManual Assertion Based On ExperimentIBA:GO_Central
RNA splicingIEA:UniProtKB-KW
Cellular Location
Nucleus
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Anti-PTBP3 antibodies

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Mouse Anti-PTBP3 Recombinant Antibody (CBYC-P739) (CBMAB-P3291-YC)

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Target: PTBP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-P739
Application*: E, IC, IH, WB
Datasheet SDS

Mouse Anti-PTBP3 Recombinant Antibody (4C9) (CBMAB-P3290-YC)

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Target: PTBP3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4C9
Application*: E, IF, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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