Mouse Anti-PTH2R Recombinant Antibody (CBYC-P762) (CBMAB-P3362-YC)

Name: Mouse Anti-PTH2R Recombinant Antibody (CBYC-P762)
SKU: CBMAB-P3362-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYC-P762

Application

WB, ICC, IHC-P, IHC-Fr, ELISA

Immunogen

Parathyroid Hormone Receptor 2

Specificity

Rat

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

PBS, pH 7.4, 0.02% sodium azide, 50% glycerol

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Parathyroid hormone 2 receptor

Introduction

PTH2R is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas.

Entrez Gene ID

81753

UniProt ID

P70555

Alternative Names

PTHR2

Function

This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity).

Biological Process

Adenylate cyclase-modulating G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cell surface receptor signaling pathwayIEA:InterPro
G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of cold-induced thermogenesisBy SimilarityISS:YuBioLab

Cellular Location

Cell membrane

Topology

Extracellular: 27-145
Helical: 146-169
Cytoplasmic: 170-176
Helical: 177-196
Extracellular: 197-237
Helical: 238-260
Cytoplasmic: 261-275
Helical: 276-297
Extracellular: 298-316
Helical: 317-337
Cytoplasmic: 338-364
Helical: 365-383
Extracellular: 384-394
Helical: 395-417
Cytoplasmic: 418-550

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-PTH2R Recombinant Antibody (CBYC-P763) (CAT#: CBMAB-P3363-YC)

Mouse Anti-PTH2R Recombinant Antibody (CBYC-P761) (CAT#: CBMAB-P3361-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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