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Mouse Anti-PTP10D Recombinant Antibody (45E10) (CBMAB-0200-CN)


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Summary

Host Animal
Mouse
Specificity
Common fruit fly
Clone
45E10
Antibody Isotype
IgG1
Application
ELISA

Basic Information

Specificity
Common fruit fly
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Ptp10D
Introduction
Protein tyrosine phosphatase 10D (Ptp10D) is a transmembrane receptor tyrosine phosphatase closely related to Ptp4E. Ptp4E-Ptp10D double mutants have lethal respiratory defects. The protein may have a role in axon outgrowth and guidance. Ptp10D regulates signaling through the Egfr, btl and Pvr receptor tyrosine kinases, and binds to sas to regulate its signaling in glia.
Entrez Gene ID
32115
UniProt ID
P35992
Alternative Names
10D; CG1817; CT4920; Dmel\CG1817; dptp; DPTP; DPTP10D; DPTP[[10D]]; Ptp10; ptp10d; ptp10D; PTP10D; R-PTP 10D
Function
May have a role in axon outgrowth and guidance.
Biological Process
Axon guidanceManual Assertion Based On ExperimentIGI:FlyBase
Branching involved in open tracheal system developmentManual Assertion Based On ExperimentIMP:FlyBase
Central nervous system developmentManual Assertion Based On ExperimentIGI:FlyBase
Long-term memoryManual Assertion Based On ExperimentIMP:FlyBase
Motor neuron axon guidanceManual Assertion Based On ExperimentIGI:FlyBase
Negative regulation of epidermal growth factor receptor signaling pathwayManual Assertion Based On ExperimentIGI:FlyBase
Negative regulation of fibroblast growth factor receptor signaling pathwayManual Assertion Based On ExperimentIGI:FlyBase
Negative regulation of vascular endothelial growth factor receptor signaling pathwayManual Assertion Based On ExperimentIGI:FlyBase
Open tracheal system developmentManual Assertion Based On ExperimentIGI:FlyBase
Protein dephosphorylationManual Assertion Based On ExperimentIDA:FlyBase
Cellular Location
Membrane
Topology
Extracellular: 43-1197
Helical: 1198-1218
Cytoplasmic: 1219-1990
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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