Mouse Anti-PTPN3 Recombinant Antibody (H-6) (CBMAB-P3437-YC)

Name: Mouse Anti-PTPN3 Recombinant Antibody (H-6)
SKU: CBMAB-P3437-YC
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

H-6

Application

WB, IP, IF, ELISA

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Protein tyrosine phosphatase, non-receptor type 3

Introduction

PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta.

Entrez Gene ID

5774

UniProt ID

P26045

Alternative Names

PTP-H1; PTPH1

Function

May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.

Biological Process

Liver regenerationIEA:Ensembl
MAPK cascadeTAS:Reactome
Negative regulation of epidermal growth factor receptor signaling pathwayTAS:Reactome
Negative regulation of membrane protein ectodomain proteolysisManual Assertion Based On ExperimentIMP:BHF-UCL
Negative regulation of mitotic cell cycleManual Assertion Based On ExperimentIDA:BHF-UCL
Protein dephosphorylationManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of membrane depolarization during action potentialManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of sodium ion transmembrane transporter activityManual Assertion Based On ExperimentIDA:BHF-UCL

Cellular Location

Cell membrane
Cytoplasm, cytoskeleton

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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