Mouse Anti-PTPRG Recombinant Antibody (CBYC-P785) (CBMAB-P3474-YC)

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Basic Information

Host Animal
Mouse
Clone
CBYC-P785
Application
WB
Immunogen
E. coli-derived Recombinant human PTP gamma/PTPRG, Ser111-Ala541
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized from PBS with trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Protein tyrosine phosphatase, receptor type G
Introduction
PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA.
Entrez Gene ID
Human5793
Mouse19270
Rat171357
UniProt ID
HumanP23470
MouseQ05909
RatF1LP13
Alternative Names
HPTPG; PTPG; R-PTP-GAMMA; RPTPG
Function
Possesses tyrosine phosphatase activity.
Biological Process
Brain developmentIEA:Ensembl
Negative regulation of epithelial cell migrationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of neuron projection developmentIEA:Ensembl
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Extracellular: 20-736
Helical: 737-762
Cytoplasmic: 763-1445
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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