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Mouse Anti-PTTG1IP Recombinant Antibody (4C11) (CBMAB-P3508-YC)

Provided herein is a Mouse monoclonal antibody against Human PTTG1 Interacting Protein. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PTTG1IP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4C11
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-180

Target

Full Name
pituitary tumor-transforming 1 interacting protein
Introduction
PTTG1IP is a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor.
Entrez Gene ID
754
UniProt ID
P53801
Alternative Names
PBF; C21orf3; C21orf1
Function
May facilitate PTTG1 nuclear translocation.
Biological Process
Negative regulation of DNA damage response, signal transduction by p53 class mediatorManual Assertion Based On ExperimentIMP:MGI
Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediatorManual Assertion Based On ExperimentIMP:MGI
Positive regulation of protein ubiquitinationManual Assertion Based On ExperimentIDA:MGI
Protein import into nucleusManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Membrane
Cytoplasm
Nucleus
According to PubMed:10781616, it is found in the cytoplasm and the nucleus.
Topology
Extracellular: 33-96
Helical: 97-117
Cytoplasmic: 118-180
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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