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Mouse Anti-PTX3 Recombinant Antibody (2B10) (CBMAB-A7252-LY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
2B10
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
PTX3 (NP_002843, 282 a.a. ~ 380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
pentraxin-related gene, rapidly induced by IL-1 beta
Entrez Gene ID
Human5806
Mouse19288
Rat689388
UniProt ID
HumanP26022
MouseP48759
RatP81062
Alternative Names
TNFAIP5; TSG-14
Function
Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
Biological Process
Extracellular matrix organizationIEA:Ensembl
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Innate immune responseManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation by host of viral exo-alpha-sialidase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation by host of viral glycoprotein metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation by host of viral processManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of exo-alpha-sialidase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of glycoprotein metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of viral entry into host cellManual Assertion Based On ExperimentIDA:BHF-UCL
OpsonizationIEA:Ensembl
Ovarian cumulus expansionIEA:Ensembl
Positive regulation of nitric oxide biosynthetic processIEA:Ensembl
Positive regulation of phagocytosisIEA:Ensembl
Response to yeastIEA:Ensembl
Cellular Location
Secreted
PTM
Glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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