PTX3

This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes.
Full Name
pentraxin-related gene, rapidly induced by IL-1 beta
Function
Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
Biological Process
Extracellular matrix organizationIEA:Ensembl
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Innate immune responseManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation by host of viral exo-alpha-sialidase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation by host of viral glycoprotein metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation by host of viral processManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of exo-alpha-sialidase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of glycoprotein metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of viral entry into host cellManual Assertion Based On ExperimentIDA:BHF-UCL
OpsonizationIEA:Ensembl
Ovarian cumulus expansionIEA:Ensembl
Positive regulation of nitric oxide biosynthetic processIEA:Ensembl
Positive regulation of phagocytosisIEA:Ensembl
Response to yeastIEA:Ensembl
Cellular Location
Secreted
PTM
Glycosylated.
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Anti-PTX3 antibodies

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Recombinant Mouse Anti-PTX3 Antibody (CBHb102) (CBMAB-Hb862-LY)

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Target: PTX3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBHb102
Application*: FC, IHC-F, FuncS, Immuno assays, WB
Datasheet SDS

Mouse Ptx3 ELISA Kit (V2LY-0626-LY2845)

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Target: Ptx3
Sensitivity: 0.052 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

Human PTX3 ELISA Kit (V2LY-0626-LY2169)

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Target: PTX3
Sensitivity: 0.05 ng/mL
Detection Range: 0.1-30 ng/mL
Sample Type: Serum, Plasma, Urine, Ascites, Cerebrospinal fluid, Tissue
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Human Recombinant PTX3 protein, His Tag (V2LY-0526-LY6103)

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Target: PTX3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-381
Tag: His Tag
Datasheet SDS

Rabbit Anti-PTX3 Recombinant Antibody (
10D9) (V2LY-0725-LY1571)

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Target: PTX3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 10D9
Application*: E, F
Datasheet SDS

Mouse Anti-PTX3 Recombinant Antibody (5B7) (CBMAB-A7253-LY)

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Target: PTX3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5B7
Application*: WB, E
Datasheet SDS

Mouse Anti-PTX3 Recombinant Antibody (2B10) (CBMAB-A7252-LY)

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Target: PTX3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 2B10
Application*: WB, E
Datasheet SDS

Mouse Anti-PTX3 Recombinant Antibody (CBFYA-0237) (CBMAB-X0350-FY)

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Target: PTX3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBFYA-0237
Application*: F, C, FN, IA, WB
Datasheet SDS

Rat Anti-PTX3 Recombinant Antibody (CBFYA-0184) (CBMAB-X0263-FY)

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Target: PTX3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYA-0184
Application*: F, C, IA, IF, IP, P, WB
Datasheet SDS

Rat Anti-PTX3 Recombinant Antibody (CBFYA-0183) (CBMAB-X0262-FY)

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Target: PTX3
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYA-0183
Application*: F, FN, IA, WB
Datasheet SDS

Mouse Anti-PTX3 Recombinant Antibody (CBYC-P795) (CBMAB-P3511-YC)

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Target: PTX3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: CBYC-P795
Application*: E, WB, IF
Datasheet SDS

Rat Anti-PTX3 Recombinant Antibody (11C146) (CBMAB-P3510-YC)

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Target: PTX3
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: 11C146
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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