PTX3

This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes.

pentraxin-related gene, rapidly induced by IL-1 beta

Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.

Extracellular matrix organizationIEA:Ensembl
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Innate immune responseManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation by host of viral exo-alpha-sialidase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation by host of viral glycoprotein metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation by host of viral processManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of exo-alpha-sialidase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of glycoprotein metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of viral entry into host cellManual Assertion Based On ExperimentIDA:BHF-UCL
OpsonizationIEA:Ensembl
Ovarian cumulus expansionIEA:Ensembl
Positive regulation of nitric oxide biosynthetic processIEA:Ensembl
Positive regulation of phagocytosisIEA:Ensembl
Response to yeastIEA:Ensembl

Secreted

Glycosylated.