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Mouse Anti-PXK Recombinant Antibody (4D11) (CBMAB-P3553-YC)

Provided herein is a Mouse monoclonal antibody against Human PX domain containing serine/threonine kinase like. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PXK antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4D11
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
PXK (AAH14479.1, 351-450 aa) partial recombinant protein with GST tag. Immunogen sequence: PDSVPVDSFP PAPSMAVVAV LESTLSCEAC KNGMPTISRL LQMPLFSDVL LTTSEKPQFK IPTKLKEALR IAKECIEKRL IEEQKQIHQH RRLTRAQSHH
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 351-450

Target

Full Name
PX domain containing serine/threonine kinase
Introduction
PXK (PX Domain Containing Serine/Threonine Kinase Like) is a protein coding gene. Diseases associated with PXK include Systemic Lupus Erythematosus. Gene Ontology annotations related to this gene include transferase activity, transferring phosphorus-containing groups and nucleotide binding.
Entrez Gene ID
54899
UniProt ID
Q7Z7A4
Alternative Names
MONaKA
Function
Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.
Biological Process
Inflammatory responseManual Assertion Based On ExperimentIMP:UniProtKB
Modulation of chemical synaptic transmissionISS:UniProtKB
Negative regulation of ATP-dependent activityManual Assertion Based On ExperimentISS:UniProtKB
Negative regulation of ion transportManual Assertion Based On ExperimentISS:UniProtKB
Cellular Location
Cytoplasm
Cell membrane
Also associates with the plasma membrane. Isoform 3 is present throughout the cell.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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