Mouse Anti-PXK Recombinant Antibody (4D11) (CBMAB-P3553-YC)

Name: Mouse Anti-PXK Recombinant Antibody (4D11)
SKU: CBMAB-P3553-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

4D11

Application

ELISA, WB

Immunogen

PXK (AAH14479.1, 351-450 aa) partial recombinant protein with GST tag. Immunogen sequence: PDSVPVDSFP PAPSMAVVAV LESTLSCEAC KNGMPTISRL LQMPLFSDVL LTTSEKPQFK IPTKLKEALR IAKECIEKRL IEEQKQIHQH RRLTRAQSHH

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 351-450

More Infomation

Target

Full Name

PX domain containing serine/threonine kinase

Introduction

PXK (PX Domain Containing Serine/Threonine Kinase Like) is a protein coding gene. Diseases associated with PXK include Systemic Lupus Erythematosus. Gene Ontology annotations related to this gene include transferase activity, transferring phosphorus-containing groups and nucleotide binding.

Entrez Gene ID

54899

UniProt ID

Q7Z7A4

Alternative Names

MONaKA

Function

Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.

Biological Process

Inflammatory responseManual Assertion Based On ExperimentIMP:UniProtKB
Modulation of chemical synaptic transmissionISS:UniProtKB
Negative regulation of ATP-dependent activityManual Assertion Based On ExperimentISS:UniProtKB
Negative regulation of ion transportManual Assertion Based On ExperimentISS:UniProtKB

Cellular Location

Cytoplasm
Cell membrane
Also associates with the plasma membrane. Isoform 3 is present throughout the cell.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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