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Mouse Anti-PYCR3 Recombinant Antibody (4F11) (CBMAB-A7273-LY)

The product is antibody recognizes PYCRL. The antibody 4F11 immunoassay techniques such as: WB, ELISA.
See all PYCR3 antibodies
Published Data
Fig.1 Western blot analysis of PYCRL protein levels in NHLFs treated with TGF-β for the indicated intervals.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
4F11
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
PYCRL (NP_075566, 32 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Pyrroline-5-carboxylate reductase 3
Entrez Gene ID
65263
UniProt ID
Q53H96
Alternative Names
FLJ13852
Function
Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline.
Biological Process
L-proline biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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