PYCR3

PYCR3 is a protein that belongs to the pyrroline-5-carboxylate reductase family of enzymes. Members of this family catalyze the final step in proline biosynthesis, converting pyrroline-5-carboxylate to proline. Glutamate and ornithine are precursors in the synthesis of proline. The protein encoded by this gene is a cytoplasmic enzyme involved in the biosynthesis of proline from ornithine.

Full Name

Pyrroline-5-carboxylate reductase 3

Function

Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline.

Biological Process

L-proline biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cytoplasm

Anti-PYCR3 antibodies

Mouse Anti-PYCR3 Recombinant Antibody (1C11) (CBMAB-P3568-YC)

Datasheet

SDS

Target: PYCR3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1C11

Application*: F, IF, IH, WB

Mouse Anti-PYCR3 Recombinant Antibody (2E10) (CBMAB-P3569-YC)

Datasheet

SDS

Target: PYCR3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2E10

Application*: IF, WB

Mouse Anti-PYCR3 Recombinant Antibody (3B9) (CBMAB-P3570-YC)

Datasheet

SDS

Target: PYCR3

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 3B9

Application*: F, IF, P, WB

Mouse Anti-PYCR3 Recombinant Antibody (4F11) (CBMAB-A7273-LY)

Datasheet

SDS

Target: PYCR3

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4F11

Application*: WB, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)