Mouse Anti-PYGB Recombinant Antibody (6G5) (CBMAB-G6488-LY)

Name: Mouse Anti-PYGB Recombinant Antibody (6G5)
SKU: CBMAB-G6488-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

6G5

Application

ELISA, WB

Immunogen

Recombinant full length protein (Human)

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Preservative

0.1% sodium azide

Concentration

5.5 mg/mL

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Glycogen Phosphorylase, Muscle Associated

Introduction

The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.

Entrez Gene ID

5834

UniProt ID

P11216

Alternative Names

GPBB

Function

Glycogen phosphorylase that regulates glycogen mobilization (PubMed:27402852).
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228).
Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228).
However, all known phosphorylases share catalytic and structural properties (PubMed:3346228).

Biological Process

Glycogen catabolic processManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

azurophil granule lumen
cytoplasm
extracellular exosome
extracellular region
membrane

PTM

Phosphorylated (PubMed:27402852).
Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A (By similarity).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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