PYGB
PYGB (Glycogen Phosphorylase B) is a protein coding gene. Diseases associated with PYGB include Myocardial Infarction. Among its related pathways are Galactose metabolismand Regulation of lipid metabolism Insulin signaling-generic cascades. Gene Ontology annotations related to this gene include pyridoxal phosphate binding and glycogen phosphorylase activity. An important paralog of the gene is PYGM.
Full Name
Glycogen Phosphorylase, Muscle Associated
Function
Glycogen phosphorylase that regulates glycogen mobilization (PubMed:27402852).
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228).
Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228).
However, all known phosphorylases share catalytic and structural properties (PubMed:3346228).
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228).
Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228).
However, all known phosphorylases share catalytic and structural properties (PubMed:3346228).
Biological Process
Glycogen catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
azurophil granule lumen
cytoplasm
extracellular exosome
extracellular region
membrane
cytoplasm
extracellular exosome
extracellular region
membrane
PTM
Phosphorylated (PubMed:27402852).
Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A (By similarity).
Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A (By similarity).
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Anti-PYGB antibodies
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CompareTarget: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-3300
Application*: E, IA, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-P807
Application*: E, IH
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2427
Application*: E, P
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBLG1-2424
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2423
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2422
Application*: E, P
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-2421
Application*: E
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2418
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2417
Application*: E, P
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2416
Application*: E, IH
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2413
Application*: E, P
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2412
Application*: E, IH, P
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-2408
Application*: E
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: M709145
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: M18612GP2
Application*: E, IA, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BB-1F9
Application*: WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9F5
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 8-F-313A
Application*: E
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8.F.313
Application*: E
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6G5
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5B8
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3G1
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1G6
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 17B6
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11C10
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 10H5
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-318
Application*: E
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-317
Application*: E
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-316
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 8.F.313A
Application*: E
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6F1
Application*: E, IH, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1.BB.113
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8G7
Application*: WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10D12
Application*: WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-2720
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2719
Application*: WB, IP
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2718
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-2716
Application*: E
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8-F-313
Application*: E
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2717
Application*: E, WB
Target: PYGB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2715
Application*: WB, IA
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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